E-ISSN 2537-0596 | ISSN 2537-0588
 

Original Research 


Relationship between locus of control belief and IL-6 in breast cancer patients

Azza EL-Amir, Mohamed Labib Salem, Noha Sabry, Eman Maher EL-Baiomy, Nehal EL-Mashad.

Abstract
Recent studies indicated to the immune disturbances in cancer patients in comparison with healthy individuals. Several studies suggested that individuals with external locus of control (E-LOC) have more symptoms of depression. Other studies indicated to the effective role of psychological status on the immune system. The association between E-LOC and immunity in cancer patients it is not clear. Study the relation between Rotter internal-external locus of control (I-E LOC) and God health locus of control (GHLC) and interleukin-6 (IL-6) in breast cancer patients. The study included hundred breast cancer patients and fifty healthy controls. Patients and participators responded to I-E LOC and GHLC questionnaires. Peripheral blood samples were collected to measure gene expression of IL-6 by using real time PCR. Breast cancer patients showed higher GHLC which was associated with higher level of IL-6 as compared to control subjects. By contrast, a significant inverse correlation between GHLC and IL-6 was found. However, there was no relationship between I-E LOC and IL-6. The results suggest no significant effect of LOC belief according to life on immune response against cancer, but high GHLC belief correlate with decreased IL-6. Further studies on the relations between other types of LOC and immune response in breast cancer is recommended.

Key words: Keywords: locus of control, breast cancer, IL-6.


 
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How to Cite this Article
Pubmed Style

EL-Amir A, Salem ML, Sabry N, EL-Baiomy EM, EL-Mashad N. Relationship between locus of control belief and IL-6 in breast cancer patients. JCBR. 2018; 1(1): 45-48. doi:104-1498960777


Web Style

EL-Amir A, Salem ML, Sabry N, EL-Baiomy EM, EL-Mashad N. Relationship between locus of control belief and IL-6 in breast cancer patients. http://www.jcbreg.com/?mno=271228 [Access: December 12, 2018]. doi:104-1498960777


AMA (American Medical Association) Style

EL-Amir A, Salem ML, Sabry N, EL-Baiomy EM, EL-Mashad N. Relationship between locus of control belief and IL-6 in breast cancer patients. JCBR. 2018; 1(1): 45-48. doi:104-1498960777



Vancouver/ICMJE Style

EL-Amir A, Salem ML, Sabry N, EL-Baiomy EM, EL-Mashad N. Relationship between locus of control belief and IL-6 in breast cancer patients. JCBR. (2018), [cited December 12, 2018]; 1(1): 45-48. doi:104-1498960777



Harvard Style

EL-Amir, A., Salem, . M. L., Sabry, . N., EL-Baiomy, . E. M. & EL-Mashad, . N. (2018) Relationship between locus of control belief and IL-6 in breast cancer patients. JCBR, 1 (1), 45-48. doi:104-1498960777



Turabian Style

EL-Amir, Azza, Mohamed Labib Salem, Noha Sabry, Eman Maher EL-Baiomy, and Nehal EL-Mashad. 2018. Relationship between locus of control belief and IL-6 in breast cancer patients. Journal of Cancer and Biomedical Research, 1 (1), 45-48. doi:104-1498960777



Chicago Style

EL-Amir, Azza, Mohamed Labib Salem, Noha Sabry, Eman Maher EL-Baiomy, and Nehal EL-Mashad. "Relationship between locus of control belief and IL-6 in breast cancer patients." Journal of Cancer and Biomedical Research 1 (2018), 45-48. doi:104-1498960777



MLA (The Modern Language Association) Style

EL-Amir, Azza, Mohamed Labib Salem, Noha Sabry, Eman Maher EL-Baiomy, and Nehal EL-Mashad. "Relationship between locus of control belief and IL-6 in breast cancer patients." Journal of Cancer and Biomedical Research 1.1 (2018), 45-48. Print. doi:104-1498960777



APA (American Psychological Association) Style

EL-Amir, A., Salem, . M. L., Sabry, . N., EL-Baiomy, . E. M. & EL-Mashad, . N. (2018) Relationship between locus of control belief and IL-6 in breast cancer patients. Journal of Cancer and Biomedical Research, 1 (1), 45-48. doi:104-1498960777