E-ISSN 2537-0596 | ISSN 2537-0588
 

Original Research 


ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS

YOUSRY E. Elbolkiny.

Abstract
Aim: the present work was planned to find a correlation between HCV infection and diabetes incidence in Egyptian patients by finding a possible relationship between HCV antibodies and both anti-insulin antibodies (AIAs) and pancreatic islet cell antibodies (PICAs).
The present work was planned to find a correlation between HCV infection and diabetes mellitus (DM) incidence in Egyptian patients by finding a possible relationship between HCV antibodies and both anti-insulin antibodies (AIAs) and pancreatic islet cell antibodies (PICAs). The screening results showed that the percentage of HCV patients out of 200 subjects were 35.5 and 14.5% in males and females, respectively. Also, the association between DM and HCV were 13.21 and 13.64% in men and women, respectively. The titers of antibodies in diabetic or non-diabetic patients ranged from 30 - 58 for AIAs and from 30 - 40 for PICAs, The percentage of patients with raised serum transaminases was significantly more in DM patients with positive HCV antibody (52.3%) than DM patients with negative HCV antibody (16.7%). Conclusion, it can be concluded that diabetic or non-diabetic patients with HCV might have a rise titer of the antibodies toward insulin or its secretory cells in pancreas or toward both. where are more susceptible to both HCV-infection and antibodies than women, indicating to here is a significant association between HCV infection and induction of diabetes in Egyptians.Conclusion, it can be concluded that diabetic or non-diabetic patients with hepatitis C might have a rise titer of the antibodies toward insulin or its secretory cells in pancreas or toward both. These antibodies can attack β-cells inducing insulin deficiency, arising DM incidence. It was also found that men are more susceptible to both HCV-infection and antibodies formation than women. Therefore, the results of this study indicate that there is a significant association between HCV infection and induction of diabetes in Egyptians.

Key words: HCV, DM, anti-insulin antibodies


 
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Pubmed Style

YEE, . ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS. JCBR. 2019; 1(2): 26-36.


Web Style

YEE, . ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS. http://www.jcbreg.com/?mno=3772 [Access: March 26, 2019].


AMA (American Medical Association) Style

YEE, . ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS. JCBR. 2019; 1(2): 26-36.



Vancouver/ICMJE Style

YEE, . ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS. JCBR. (2019), [cited March 26, 2019]; 1(2): 26-36.



Harvard Style

, Y. E. E. & (2019) ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS. JCBR, 1 (2), 26-36.



Turabian Style

, YOUSRY E. Elbolkiny, and . 2019. ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS. Journal of Cancer and Biomedical Research, 1 (2), 26-36.



Chicago Style

, YOUSRY E. Elbolkiny, and . "ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS." Journal of Cancer and Biomedical Research 1 (2019), 26-36.



MLA (The Modern Language Association) Style

, YOUSRY E. Elbolkiny, and . "ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS." Journal of Cancer and Biomedical Research 1.2 (2019), 26-36. Print.



APA (American Psychological Association) Style

, Y. E. E. & (2019) ASSOCIATION BETWEEN HCV INFECTION AND THE INCIDENCE OF DIABETES MELLITUS IN EGYPTIANS. Journal of Cancer and Biomedical Research, 1 (2), 26-36.